Swim-Up Method

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Medical Information

By implementing modernized treatments such as, In-Vitro Fertilization (IVF), donor programs, andrology, and fertility research, EuroCARE IVF helps intended parents become loving families.

Swim up method gender selection CyprusThe swim-up method for gender selection Cyprus is almost identical to the Percoll method — separation of X and Y-sperm is the result of the standard technique used to isolate motile sperm for use in IVF treatment in Nicosia.

As the leading fertility team in North Cyprus, we understand one’s desire to balance your family. We will do everything in our power to help you have a baby of your desired gender.

Upon request, euroCARE IVF performs the ‘swim-up’ method for gender selection — which is similar to MicroSort technologies.

The Benefits

Studies show that centrifugation causes no more DNA damage to sperm than a direct swim-up technique.

Sperm sorting is used to prevent X-linked diseases (such as hemophilia, Duchenne muscular dystrophy, Lesch-Nyhan syndrome, X-linked mental retardation) that are expressed in male babies.

Sperm sorting also decreases the chance of HIV transmission in HIV-positive males, because the virus is present in the seminal fluid rather than the sperm.

Swim-Up Method for Gender Selection

No sperm sorting method alone is 100% accurate in sorting the sperm into male and female batches — which is why our expert embryologist includes the sorting procedure as part of your PGS treatment cycle. This increases the chances of having more male or female sperm in the sample used to fertilize the eggs.

The swim-up method is approximately 70% accurate in sorting the sperm into male and female batches.  The ‘predominantly’ male or female batch is then used to fertilized the eggs.

The Process

  1. Semen is placed in a test tube; in some cases, it is previously washed and centrifuged.
  2. A culture medium is carefully placed on top of the semen. The medium is a hospitable environment for the sperm, and healthy sperm will swim up into it. Slow and immobile sperm are left behind, along with most debris in the semen.
  3. The test tube is let stand an hour or so; in some cases it is placed at an angle, and/or in an incubator.
  4. In the standard procedure, the top layer is collected for use. Using this technique for attempted male gender selection, a small fraction of the top layer is first discarded. This practice is based on the following theory:
  • a) a small fraction of X-sperm are the fastest of all
  • b) next fastest are the Y-sperm
  • c) slowest are the majority of X-sperm. The modified swim-up attempted to discard that first group of fast X-sperm.

5. The portion retained for use may be washed and centrifuged again

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