Frequently Asked Questions

faqeurocareivfDo you have questions regarding your IVF treatment in North Cyprus?

Our expert team has put together some of the most frequently asked questions that we receive at the top fertility clinic in Cyprus, euroCARE IVF.

If you do not see an answer to your question below, contact one of our journey coordinators to further assist you. Our team is readily available to help you.

Infertility FAQs

Infertility is defined as one year of actively trying to conceive without success. Generally an evaluation is encouraged in this scenario. Sometimes an evaluation is recommended much earlier, typically after six months of attempted conception, if the couple has an obvious potential fertility problem such as a history of tubal disease, menstrual irregularity, prior abnormal semen analysis, or maternal age > 35 years of age.

The first step is to discuss our program details with our Patient Coordinators — by either using our contact form, getting a free quote, or booking an appointment. You will be advised in detail the cost of treatment, tests required, and the details of our IVF process. Connecting with our team is an opportunity for you to ask questions, as it is very important for you to understand the treatment process entirely from beginning to end (and everything in between).

This is a very broad question which often requires a very complicated and in-depth discussion, especially when individualizing treatment for a patient or couple. However, in general, the treatment options include observation, lifestyle management including nutritional adjustment and exercise, intra-uterine insemination (IUI), reproductive surgery (such as hysteroscopy or laparoscopy), ovulation stimulation with oral or injectable medications, in vitro fertilization (IVF), intra-cytoplasmic sperm injection (ICSI), gender selection, and donor services.

IVF is a technology that introduces the retrieved eggs and sperm — which is combined in a specialized culture medium where the chances of successful fertilization are greatly enhanced. The embryos are observed and grown in our modernized IVF laboratory, where they are graded for quality. Once the embryos have reached the blastocyst stage, the chosen amount of embryos are reintroduced to the recipient’s uterus.

IVF is a complex ART procedure that involves multiple steps: testing, ovarian stimulation, egg & sperm collection, fertilization and embryo transfer. First, you’ll be required to do some fertility tests to establish a medical diagnosis. In the second phase, you’ll be administered fertility medication to stimulate your ovaries to produce more eggs. After a few days, our fertility doctor will collect the mature eggs and will fertilize them in our state-of-the-art lab in North Cyprus. The resulting embryo(s) will be transferred to your uterus. The procedure takes about 20 days.

Most miscarriages are caused by abnormal chromosomes in the baby. Recurrent miscarriage is three or more consecutive pregnancy losses. It is estimated that one in six, or approximately 15% of pregnancies end in miscarriage. IVF with PGT (Preimplantation Genetic Testing) is used to prevent recurrent miscarriages. The treatment refers to two types of tests that may be performed on embryos prior to transfer during IVF – Preimplantation Genetic Screening (PGS) and Preimplantation Genetic Diagnosis (PGD).

AMH (Anti-müllerian hormone) is a hormone secreted by the developing follicles in the woman’s ovaries. AMH test may be requested along with other fertility tests performed before IVF treatment to assess the ovarian reserve (egg supply) in female patients. AMH test results are a good predictor for your ovarian response to stimulation, and help our fertility doctor detect various disorders in the reproductive organs.

IVF is one of the most commonly used and successful ART procedures primarily designed to treat infertility and prevent genetic abnormalities in pre-born babies. 8 million babies were born worldwide since the first one in 1978 as a result of IVF (and other ART procedures).

Your success with IVF depends on a number of factors including age, type of infertility, previous pregnancy, lifestyle, previous IVF cycles, use of egg donors, fertility clinic, etc.

For a better insight, here you can find some statistical data for our IVF success rate in 2017:

Age ————IVF ———Egg donation

20-29 ———75% ———80%

30-34 ———65% ———80%

35-39 ———51% ———78%

40-44 ———35%———78%

45+ ———— / ————70%

IVF is a type of assisted reproductive technology used to treat infertility in women and men and address genetic issues in one or both parents. IVF may also be used in surrogacy arrangements. IVF is generally not used until less invasive or expensive options have failed or been determined unlikely to work.

IVF is generally recommended to women with blocked or removed fallopian tubes, infertility disorders like polycystic ovarian syndrome (PCOS) or endometriosis, irregular ovulation cycles, or to men with sperm abnormalities.

Some of the benefits of IVF are:

  • IVF works where other fertility treatments fail
  • It can be used by anybody
  • You can use donated eggs and/or sperm
  • You have control over timing
  • Increase your chances of having a healthy baby
  • Decrease your chances of miscarriage
  • Increase your chances of getting pregnant

IVF success depends on a number of factors, such as age, previous pregnancy, infertility issue, lifestyle, previous IVF cycles, use of donor eggs, fertility clinic, etc. However, there a number of effective ways to increase your chances for pregnancy with IVF.

 

IVF may fail for a number of reasons, such as age, medical history, lifestyle, previous pregnancy, number of IVF cycles, use of donor eggs, etc. After your IVF cycle fails, the first step is to analyze the results with our top fertility doctor in Nicosia and explore alternative treatment options or alter medication protocol. It is generally recommended a woman should try up to six cycles before giving up. If IVF is not the right treatment for you, we offer other alternative treatments for your infertility problem. Remember, pregnancy is still possible after a failed IVF treatment.

 

IVF is generally not painful. Howeve, certain stages of the IVF process may be slightly uncomfortable or painful for some patients. The pain or discomfort during IVF can be managed with pain medication.

 

First, you need to contact our patient coordinator to receive detailed information about our treatment programs. Patients are usually required to do a couple of fertility tests before starting their IVF treatmen. You’ll be administered fertility medication and the ovarian stimulation process can soon begin. After a few days, Dr. Armagan Ulubas, your fertility specialist at euroCARE IVF, will collect a few eggs from your ovaries and will fertilize them in our state-of-the-art lab in North Cyprus. After fertilization, embryos will be transferred to your uterus in order to establish a pregnancy.

 

There are a lot of variables that determine the IVF success including maternal age, egg quality, previous pregnancy, medical history, type of infertility, lifestyle, past IVF cycles, use of donor eggs, etc. After a failed IVF cycle, the first thing you should do is to consult with our fertility doctor in order to identify the reasons for the IVF failure and to recommend you an alternative treatment plan or alter your medication protocol.

 

Before trying IVF, your doctor may recommend you other alternative treatments such as clomid or IUI (Intrauterine Insemination). If these treatments are not successful or suitable for your medical condition, then you may try IVF. Studies showed that IVF gives you the best odds for getting pregnant. What’s more, IVF can even determine the causes of your unexplained infertility.

 

Yes, IVF with PGS (Preimplantation Genetic Screening) testing not only detects embryos with chromosomal abnormalities, but also helps fertility doctors select the best embryos of the desired sex.

 

Yes, IVF is generally safe. However, as for every medical procedure, there are certain risks associated with the IVF procedure, including multiple pregnancy, miscarriage,  ovarian hyperstimulation syndrome (OHSS), bleeding or infection, which all can happen quite rarely.

 

For most patients, the injections aren’t pleasant. The good thing is that they are quick and any discomfort is over in a few seconds. The discomfort or pain caused by IVF injections can be managed with medication such as paracetamol or by applying heat/cold to the affected area.

 

Women with PCOS may have difficulty getting pregnant because they do not ovulate regularly. Women with PCOS still have chances for conceiving with IVF. Overall, pregnancy and live birth rates with IVF for this group of patiens are similar to those for women with no fertility issues.

 

 

At euroCARE IVF, we offer several ways to achieve pregnancy after menopause: Tandem IVF, IVF with donor eggs, IVF with genetic testing, IVF with frozen eggs.

 

 

IVF is a popular treatment for patients after tubal ligation because there’s no need to reconnect the tubes. Our fertility doctor will first stimulate your ovaries to produce more eggs and then will collect the mature eggs directly from your ovaries in order to fertilize them in our IVF lab in Cyprus.

 

 

Studies found no link between fertility treatments like IVF and cancer, with some reporting a small increase in cancer risk for hormone-sensitive cancers including ovarian, uterine, and breast.

 

 

Implantation failure is related to either maternal or embryonic factors. Maternal factors include uterine structural abnormalities, thrombophilia, non-receptive endometrium and immunological factors. Failure of implantation due to embryonic causes occurs for embryos with genetic abnormalities or other factors that impair their ability to hatch and ultimately, to implant into the uterus lining.

 

 

IVF is an available option to women without ovaries. Egg collection can be done before the surgery or after if the ovaries remain intact. The collected eggs can be frozen and stored for future use, and when the time comes they will be fertilized in our IVf lab and implanted into a surrogate mother.

 

 

Egg Donation FAQs

Egg donation is a special program at our top fertility clinic in Cyprus that uses donor eggs to allow other women to have a baby as part of IVF or other ART procedure.

Donors are first screened to make sure they are completely healthy. After the selection is carefully made, our donors are matched to our patients and the egg donation process can begin. Donors are administered fertility medication to produce multiple eggs, which are collected and fertilized with the father’s (or donor) sperm in our state-of-the-art lab.

Potential donors have to meet the following qualifying criteria:

  • Between 21-28 years of age
  • Have regular monthly periods
  • No reproductive disorders or abnormalities
  • Physically and emotionally healthy
  • BMI under 28
  • Non-Nicotine user, non-smoker, non-drug user
  • Not currently on the Depo-Provera shot
  • Not currently using the Implanon/Nexplanon arm implant
  • Willing to undergo medical and psychological evaluation
  • Willing to take injectable medication
  • Willing to commit to the process for a minimum of 6 months
  • Other requirements

Egg donation involves multiple steps: donor selection and cycle synchronization, egg collection, sperm collection, fertilization using ICSI, embryo transfer, embryo freezing (done upon request).

Egg donation can take approx one month.

Couples using donor eggs usually bear all costs. Typically, they’ll be paying for your own procedure, as well as for the medical expenses, including any additional expenses due to complications that may arise from the egg retrieval process. In case the recipient doesn’t get pregnant with the first treatment, donors may be asked to donate eggs a second time.

Egg donation is generally a painless process although certain stages of the IVF process can cause discomfort or even pain, which still can be managed with medication.

Good candidates for IVF with donor eggs are:

  • Women with premature ovarian failure (early menopause)
  • Women with diminished ovarian reserve (after 40)
  • Women with genetic diseases
  • Women with multiple failed IVF cycles

The top fertility center in North Cyprus offers a renowned IVF with egg donation program that meets the highest standards set by the European Society of Human Reproduction and Embryology. All egg donors are required to undergo a rigorous screening procedure before they are permitted to donate at our IVF center in Cyprus.

Our success rates for IVF with egg donation in 2018 were as follows:

 

Age –———Egg donation

20-29———80%

30-34 ———80%

35-39———78%

40-44———78%

45+ ———–70%

IVF with donor eggs may failure may be caused due to poor egg, embryo or sperm quality, implantation problem, medication side effects, thin uterine lining.

Egg donors can be  known (friends, family members) or anonymous (select from our extensive database of global, anonymous egg donors). In both cases, egg donors are always required to undergo a thourough screening process in order to qualify for our egg donation program in Cyprus.

Yes, egg donation is generally safe. A collection of studies of over 180,000 women found no evidence of increased risk for ovarian cancer after ovarian stimulation. Some egg donors may experience side effects caused by fertility medication. Egg donation may be emotionally challenging for both parents and egg donors. Some of the risks for women using donor eggs are miscarriage and multiples.

Egg Collection FAQs

Ovulation induction may last for approximately 12 days.

Dr. Armagan will prescribe the correct dose of stimulation medication for you from the results of the blood test and Antral follicle scan.  At this stage he will also advise if a further scan or tests are required during the stimulation phase before coming to Cyprus.

Ovarian response to the stimulation medication is monitored

The number of eggs collected depends on each individual patient’s fertility levels and ovarian reserve.  The Ultrasound scan which Dr. Armagan will carry out on your first appointment will allow him to see how well your follicles have developed and be able to give you an indication then of how many eggs you are likely to produce.  For example our donors being young and fertile will produce 10-20 eggs.  In addition, the number of embryos created depends on how many eggs produced and the quality of the sperm used.

Yes you will be sedated for the procedure and not feel any pain.  You may have some spotting and cramping afterwards though this is perfectly normal.

Embryo Transfer FAQs

Embryos are typically transferred 3 days after fertilization and may then be at the eight-cell stage, or they are transferred 5 days after fertilization when they have reached the blastocyst stage.

A blastocyst embryo is one which has developed for 5 days after fertilization.   Not all embryos will develop to produce blastocysts.  Our embryologist may advise it is safer to consider a day three embryo transfer than risk having no blastocyst to transfer on day five.   Blastocyst transfer is typically an option for women who produce 10+ eggs.

Before an embryo can attach to the wall of the womb, it has to break free or ‘hatch’ from its outer layer which is called the zona pellucida.  Assisted hatching is when a hole is made or the outer layer is thinned helping the embryos to ‘hatch’ to increase the chances of pregnancy.  We do carry out Assisted Hatching at euroCARE IVF if it is required typically so in women 35+ years or when the embryos have a thick zona pellucida.  Assisted hatching is also used when a patient has a history of failed IVF cycles.

Embryo grading is carried out by our embryologist along with information such as the patients age, fertility history and other information to determine the optimal day of transfer, the appropriate number and exactly which embryos to transfer.  It is performed according to the number and appearance of the cells.

As embryos divide, sometimes a small portion of cytoplasm (the inside of the cell) breaks off and forms what we call a fragment. Fragments do not contain nuclei and are not considered cells. The causes of fragmentation are poorly understood, but embryos containing a lot of fragmentation are developmentally disadvantaged simply because the cells lose too much cytoplasm and thus, cellular machinery, to the fragments.

If you have a number of good quality embryos left that are not transferred, then there is the option to freeze them. These can be used in a cycle at a later date in case the first cycle is unsuccessful, or if you decide you wish to have more children in the future.  Dr. Armagan will advise regarding the quality and quantity remaining and let you know if it would be beneficial for you.

Some patients on a tight time scale do travel home the evening after their transfer however we advise to wait until at least the following day before flying home. Flying or any other mode of transportation has not been shown to have any adverse effects on embryo transfer.

As with any medication taken there can be some side effects however it is quite rare that patients notify us of any.  The side effects will be noted on the medication information leaflet.  If you do experience any then we advise you to let us know straight away so Dr Armagan can advise.

Every patient responds to the ovarian stimulation differently therefore a risk relating to the IVF procedure may be that it has to be cancelled due to poor ovarian response or ovarian hyper-stimulation. Also if the male partner does not produce any quality sperm in his sample or through a testicular biopsy procedure then the treatment may also need to be cancelled. In any case Dr. Armagan will advise the best way forward for you such as egg or sperm donation.

The initial tests we ask you to do before commencing IVF treatment (Antral Follicle Scan, Hormone tests and sperm analysis) will however give Dr. Armagan a very good idea from the start of your chances of IVF treatment using your own eggs and sperm. He will therefore be able to advise at that time if he feels a different route would be best to achieve pregnancy, thus saving the disappointment of any cancellations.

Most women will naturally worry about the risk of failure and that they may end up doing something which will influence the result. Once the embryos are transferred to the uterus they are safe there so please don’t be worried if you cough or sneeze.  It can be very hard to deal with the uncertainty and anxiety of the 2 week wait. The emotional stress can be immense and lying in bed all day will just exacerbate this so please carry on your normal day to day activities as much as possible.

Do…

  • Take your medication properly.
  • Continue with your everyday normal activity
  • Eat plenty of fresh fruits, vegetables and salad
  • Surround yourself with people who will make you feel relaxed and happy and avoid those who may raise your insecurity and stress levels

Do not…

  • Use a sauna, hot tub / bath (a shower is fine) or do any vigorous activity (like strenuous exercise)  which could raise your body temperature
  • Have sex for 12 days after transfer
  • Sunbathe or swim in the sea or public pool
  • Smoke, take drugs or drink alcohol
  • Take any additional medication without speaking with Dr Armagan first
  • Do anything which you are not comfortable with (this will help to avoid self-blame if the IVF cycle does not succeed).

The transfer process is very smooth and most patients do not experience any bleeding or spotting after their transfer however if you do it is nothing to worry about.  A reason for some spotting could be because you have a narrow cervical opening.  The blood is not coming from your uterus and your embryos are not affected in any way. The tiny drop of blood is not your embryo so you should keep calm and carry on with your everyday activity.   In the extremely unlikely event that you experience heavy bleeding after the transfer then you should let us know immediately.

During embryo transfer Dr. Armagan cleans your vaginal canal and the cervix with a sterile fluid. After the embryo transfer you might experience a wet feeling, which is just this fluid leaking out.  There is no need to panic thinking it is your embryos, the fluid is not from your uterus where your embryos have been transferred and remain safe inside.

General FAQs

No smoking, diet and nutrition have been shown to increase a couple’s chances of conception.  For example, foods containing zinc (oysters), Vitamin E (eggs), Vitamin C (Oranges, strawberries, grapefruits, cherries),  Folic Acid (spinach and dark leafy green vegetables), Brazil nuts, Wholegrain (bread, cereals & crackers), Decaffeinated beverages and water have all been shown to increase sperm count and motility.

It is possible to use a combined contraceptive pill in order to regulate your menstrual cycle and in turn control the timing of your treatment.  The pill is taken for 21 days then you break for 7 days.  When you stop the pill on day 21 your period will begin approx. 3-4 days later.  You then begin the new pill cycle after the 7 day break thus regulating your cycle to 28 days.  We can then plan ahead for your treatment date.

Absolutely. Women who no longer have a monthly period can still come for egg/embryo donation treatment. We have no age restrictions at euro IVF.

Yes you can use your own egg donor however the donor will need to have all the normal fertility blood tests and scans to see if she has enough eggs for the treatment. You will also need to synchronize your periods.  The results will need to be sent to Dr. Armagan to advise whether it is possible or not.

No, all the eggs that are retrieved during egg collection are exclusively yours.

Dr. Armagan will ensure your donor is in sync with your cycle.  When you advise your menstrual cycle/medication has started marking the beginning of your treatment process, your donor will begin her stimulation process in Cyprus.

There are no guarantees when it comes to twins as implantation is determined by nature and occurs 2-3 days after embryo transfer.  In order to increase your chances of having twins we can transfer 3 or 4 of the best quality embryos in the hope that more than one of them will implant.

Medication FAQs

The cost of the medication entirely depends on your own personal circumstances.  Once Dr. Armagan has reviewed your test results and determined the dose you require then we will be able to estimate the cost.  Similarly with the medication required during and after treatment, this will depend on what Dr. Armagan prescribes once he has carried out your initial scan and the treatment in Cyprus.

Dr. Armagan will organize a prescription for the medication you are required to take at home in preparation for the treatment in Cyprus. You can buy this medication from your local pharmacy or we work with a pharmacy in the UK that can deliver the medication to you. Medication required during your treatment in Cyprus will be prescribed and bought from a pharmacy here.

We will give you full information on the medication you are required to take after the transfer procedure. Naturally this may vary from patient to patient. If you have positive result then there is medication you need to take until 12 weeks gestation. We can supply the medication for you in Cyprus (at your own cost) if you wish or we can organize a prescriptıon for you so you can buy the medication when you are home. As long as you pack the medication in your hold luggage and not in your carry-on luggage then there will be no problem at the airport.

Once you have decided on your treatment then we advise you to start taking 75mg aspirin, 400mcg folic acid and a multi-vitamın daily.

Gender Selection FAQs

Yes, gender selection is possible and completely legal in Cyprus. At euroCARE IVF we use two methods of gender selection in IVF:

PGS (Preimplantation Genetic Screening) and Sperm Swim Up. PGS is performed after fertilization in order to select the best embryo of the desired sex. Sperm Swim Up is done before fertilization in a procedure that involves centrifugation of the sperm sample and sorting it out into female and male batches.

Yes, PGS (Preimplantation Genetic Screening) and Sperm Swim Up, both methods used for gender selection in IVF at euroCARE IVF Cyprus, are considered a safe practice as they proved to be extremely helpful in the selection of best sperm for fertilization or the best embryo(s) for implantation.

Gender selection is a medical procedure that allows parents to choose the gender (sex) of their baby. There are two gender selection methods in IVF Cyprus – PGS and Sperm Swim-Up. PGS (Preimplantation Genetic Screening) is performed on day 3 or day 5 of embryo development to detect chromosomal abnormalities in embryos and transfer only the best one(s) into your uterus. With sperm swim-up, gender selection is done by sorting out the sperm sample into female and male batches to attempt fertilizing the eggs with the X- or Y-bearing sperm.

Gender selection Cyprus is a highly successful fertility treatment at euroCARE IVF, with PGS (Preimplantation Genetic Screening) reaching 98% accuracy and sperm swim up exceeding 86% for both male and female babies.

Upon request, euroCARE IVF performs the ‘swim-up’ method for gender selection in IVF or artificial insemination (IUI). Swim up, similar to MicroSort ® technology, is a sperm sorting method that sorts out the sperm sample in two layers, one with  X-sperm (female child), the other with Y-sperm (male child).

Gender selection is a controversial topic around the world mostly due to some the misconceptions associated with it. Gender selection may be used in cases when the babies are at risk of developing a genetic disorder. Gender selection is also done to prevent miscarriage or further complications due to embryonic factors.

Sperm Donation FAQs

Sperm donation is the procedure in which a man (donor) donates semen to help infertile individuals or couples have a baby.

Along with donor qualification and screening process, sperm donation Cyprus follows the same steps as in a regular IVF treatment: fertility testing, ovarian stimulation, egg collection, donor sperm collection, fertilization, and embryo transfer. Donor sperm is collected the same day when egg collection is performed at our IVF center in North Cyprus.

Selection of sperm donors is made based on good health status and absence of genetic abnormalities. On average, only about 5% of all applicants meet the requirements to donate.

People who cannot participate in our sperm donation program in Cyprus are:

  1. Carriers of certain diseases such as cystic fibrosis, sickle cell anemia, etc.
  2. Homosexual men and men who have had sex with other men
  3. Intravenous drug users
  4. Men at risk for HIV infection

While the identity of sperm donors is kept anonymous, a lot of other information is available to the recipient:

  • age
  • nationality
  • height
  • weight
  • blood type
  • skin colour
  • hair colour
  • eye colour
  • educational background
  • previous donation history

If you need a sperm donor, one will be provided by euroCARE IVF team. We will maket he selection and then the mathing based on your preference for eye and hair color, weight, height, skin colour, occupation, education, specific nationality, etc.

Sperm donation in North Cyprus is an excellent option for couples affected by male infertility such as varicoceles, low sperm count or low sperm motility.

IUI FAQs

Intrauterine insemination (IUI) is a fertility treatment that involves injecting sperm inside the woman’s uterus to facilitate fertilization.  The goal of IUI is to increase the number of sperm that reach the fallopian tubes and subsequently increase the chances of pregnancy.

Good candidates for IUI treatment are:

  • Women with ovulatory disorders
  • Women with mild endometriosis
  • Women with unexplained infertility

It is important to remember that IUI success rates also depend on the sperm count. Sperm counts between 20 and 30 million/ml of semen are ideal for sperm washing and subsequent IUI treatment.

Women often have a 10 to 20 percent chance of getting pregnant with just one IUI cycle. The more IUI cycles you undergo, the higher the chance is for a pregnancy. With 3 to 6 cycles of IUI, pregnancy rates can be as high as 80 percent. However, our fertility doctor may recommend you IVF if your chances for success with IUI are too low.

The IUI procedure should only take a few minutes and it shouldn’t hurt. Some mild discomfort may occur when the speculum is inserted, or you may experience cramping when the catheter passes through the cervix. You’ll be sedated and under pain medication during the procedure.

IUI with fertility medication (Clomid): average success rates range from 8% to 15% per cycle for patients under 35 and 2% to 5% for patients over 40. IVF using a woman’s own eggs: average success rates range from 40% to 45% for patients under 35 to 15% or less for women over 42. Whether IUI or IVF is better for you, depends on your medical condition and chances for success with each treatment.

Most side effects are caused by the fertility drugs taken during the IUI cycle, but not the IUI procedure itself. The side effects are mild in intensity and disappear once you stop taking fertility drugs.

After 40, your chance of becoming pregnant are 5%. At euroCARE IVF Cyprus, we offer other possibilities to women over 40 to increase their chances for success: Tandem IVF, IVF with egg donation, IVF with genetic testing, IVF with frozen eggs. The success rate of IVF with Egg donation for patients over 40 in 2018 at euroCARE IVF was 78%.

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